The Institute of Virology at the Technical University of Munich (TUM), in collaboration with the Proteomics Core Facility, is seeking a highly motivated postdoctoral fellow to join our research team. This position focuses on mass spectrometry-based multi-omics analysis in the field of virus-host interactions.

The position is initially funded for two years, with the possibility of extension based on secured funding from the German Center for Infection Research (DZIF).

Your Role
You will be part of an enthusiastic research team investigating antiviral immunity and virus-host interactions through multi-omics analysis of infected cells, tissues, ex-vivo organs, and biological fluids. Our goal is to uncover fundamental principles of cell-intrinsic antiviral immunity and identify host factors that can serve as potential therapeutic targets.

As the primary expert in proteomics analysis, you will play a key role in the laboratory, leading research projects and driving innovations in mass spectrometry-based proteomics.

Key Responsibilities
• Investigate the effects of type-I interferons and virus infections on cells and tissues using advanced LC-MS/MS systems.
• Maintain and optimize modern liquid chromatography-tandem mass spectrometry (LC-MS/MS) instrumentation.
• Develop and implement state-of-the-art proteomics technologies, including:
 o High-throughput proteomics
 o Low-input protein MS analysis
 o Spatial proteomics and deep visual proteomics (DVP)
 o Post-translational modification (PTM) analysis
• Work closely with the Proteomics Core Facility to ensure cutting-edge mass spectrometry workflows.

Your Profile
• PhD in biochemistry, biotechnology, engineering, cell biology, or a related field.
• Proven experience in LC-MS/MS operation, maintenance, and data analysis.
• Strong background in MS-based proteomics data analysis and familiarity with modern computational tools.
• Additional experience in high-throughput proteomics, low-input proteomics, DVP, image analysis, and laser dissection microscopy is a plus.
• Familiarity with clinical proteomics is advantageous.
• Strong teamwork, enthusiasm for proteomics research, and excellent communication skills are essential.

What We Offer
• Full-time position based on the TV-L E13 pay scale (adjusted for prior experience).
• Initial funding for two years, with planned extension.
• Involvement in cutting-edge research at the forefront of antiviral immunity and virus-host interactions.
• Collaborative and international research environment.
• Access to state-of-the-art proteomics facilities, including a well-equipped mass spectrometry and computational infrastructure.
• Work in Munich, one of the most liveable and vibrant cities in the world.

Application Process
To apply, please email your application as a single PDF file with the subject line “MS-Proteomics” to Tatjana Polat (tatjana.polat@tum.de) by March 31, 2025.

Your application should include:
1. Motivation letter highlighting your qualifications and research interests.
2. Curriculum Vitae (CV), including a list of publications.
3. Contact information for two referees.

Contact for Further Inquiries
For additional questions, please reach out to:
Prof. Andreas Pichlmair (andreas.pichlmair@tum.de)

More information about our research can be found on this site, and the homepage of Proteomics Facility – Translational Medicine.