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Immunopathology of Virus Infections

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Featured

Multilevel Proteomics Reveals Host Perturbations by SARS-CoV-2 and SARS-CoV

A. Stukalov, V. Girault, V. Grass, O. Karayel, V. Bergant, C. Urban, D.A. Haas, Y. Huang, L. Oubraham, A. Wang, M.S. Hamad, A. Piras, F.M. Hansen, M.C. Tanzer, I. Paron, L. Zinzula, T. Enghleitner, M. Reinecke, T.M. Lavacca, R. Ehmann, R. Wölfel, J. Jores, B. Kuster, U. Protzer, R. Rad, J. Ziebuhr, V. Thiel, P. Scaturro, M. Mann, A. Pichlmair

Multilevel Proteomics Reveals Host Perturbations by SARS-CoV-2 and SARS-CoV Journal Article

In: Nature, 2021, ISSN: 0028-0836.

Abstract | Links | BibTeX

A Protein-interaction Network of Interferon-stimulated Genes Extends the Innate Immune System Landscape

P. Hubel, C. Urban, V. Bergant, W.M. Schneider, B. Knauer, A. Stukalov, P. Scaturro, A. Mann, L. Brunotte, H.H. Hoffmann, J.W. Schoggins, M. Schwemmle, M. Mann, C.M. Rice, A. Pichlmair

A Protein-interaction Network of Interferon-stimulated Genes Extends the Innate Immune System Landscape Journal Article

In: Nat. Immunol., 2019, ISSN: 1529-2916.

Abstract | Links | BibTeX

An Orthogonal Proteomic Survey Uncovers Novel Zika Virus Host Factors

P. Scaturro, A. Stukalov, D.A. Haas, M. Cortese, K. Draganova, A. Płaszczyca, R. Bartenschlager, M. Götz, A. Pichlmair

An Orthogonal Proteomic Survey Uncovers Novel Zika Virus Host Factors Journal Article

In: Nature, 2018, ISSN: 1476-4687.

Abstract | Links | BibTeX

Oxeiptosis, a ROS-induced Caspase-independent Apoptosis-like Cell-death Pathway

C. Holze, C. Michaudel, C. Mackowiak, D.A. Haas, C. Benda, P. Hubel, F.L. Pennemann, D. Schnepf, J. Wettmarshausen, M. Braun, D.W. Leung, G.K. Amarasinghe, F. Perocchi, P. Staeheli, B. Ryffel, A. Pichlmair

Oxeiptosis, a ROS-induced Caspase-independent Apoptosis-like Cell-death Pathway Journal Article

In: Nat. Immunol., vol. 19, no. 2, pp. 130-140, 2017.

Abstract | Links | BibTeX

72 entries « 1 of 2 »

2022

M.I. Hollenhorst, R. Nandigama, S.B. Evers, I. Gamayun, N.A. Wadood, A. Salah, M. Pieper, A. Wyatt, A. Stukalov, A. Gebhardt, W. Nadolni, W. Burow, C. Herr, C. Beisswenger, S. Kusumakshi, F. Ectors, T.I. Kichko, L. Hübner, P. Reeh, A. Munder, S. Wienhold, M. Witzenrath, R. Bals, V. Flockerzi, T. Gudermann, M. Bischoff , P. Lipp, S. Zierler, V. Chubanov, A. Pichlmair, P. König, U. Boehm, G. Krasteva-Christ

Bitter Taste Signaling in Tracheal Epithelial Brush Cells Elicits Innate Immune Responses to Bacterial Infection Journal Article

In: The Journal of Clinical Investigation, vol. 132, no. 13, 2022, ISSN: 1558-8238.

Abstract | Links | BibTeX

M.C. Serrero, V. Girault, S. Weigang, T.M. Greco, A. Ramos-Nascimento, F. Anderson, A. Piras, A.H. Martinez, J. Hertzog, A. Binz, A. Pohlmann, U. Prank, J. Rehwinkel, R. Bauerfeind, I.M. Cristea, A. Pichlmair, G. Kochs, B. Sodeik

The Interferon-inducible GTPase MxB Promotes Capsid Disassembly and Genome Release of Herpesviruses Journal Article

In: eLife, vol. 11, pp. e76804, 2022, ISSN: 2050-084X.

Abstract | Links | BibTeX

S. Ambike, C. Cheng, M. Feuerherd, S. Velkov, D. Baldassi, S.Q. Afridi, D. Porras-Gonzalez, X. Wei, P. Hagen, N. Kneidinger, M.G. Stoleriu, V. Grass, G. Burgstaller, A. Pichlmair, O.M. Merkel, C. Ko, T. Michler

Targeting Genomic SARS-CoV-2 RNA with siRNAs Allows Efficient Inhibition of Viral Replication and Spread Journal Article

In: Nucleic Acids Research, vol. 50, no. 1, pp. 333-349, 2022, ISSN: 0305-1048.

Abstract | Links | BibTeX

Q. Emslander, K. Vogele, P. Braun, J. Stender, C. Willy, M. Joppich, J.A. Hammerl, M. Abele, C. Meng, A. Pichlmair, C. Ludwig, J.J. Bugert, F.C. Simmel, G.G. Westmeyer

Cell-free Production of Personalized Therapeutic Phages Targeting Multidrug-resistant Bacteria Journal Article

In: Cell Chemical Biology, 2022, ISSN: 2451-9456.

Abstract | Links | BibTeX

G. Jocher, V. Grass, S.K. Tschirner, L. Riepler, S. Breimann, T. Kaya, M. Oelsner, S.M. Hamad, L.I. Hofmann, C.P. Blobel, C.B. Schmidt-Weber, O. Gokce, C.A. Jakwerth, J. Trimpert, J. Kimpel, A. Pichlmair, S.F. Lichtenthaler

ADAM10 and ADAM17 Promote SARS-CoV-2 Cell Entry and Spike Protein-mediated Lung Cell Fusion Journal Article

In: EMBO reports, vol. 23, no. 6, pp. e54305, 2022.

Abstract | Links | BibTeX

K.I. Wagner, L.M. Mateyka, S. Jarosch, V. Grass, S. Weber, K. Schober, M. Hammel, T. Burrell, B. Kalali, H. Poppert, H. Beyer, S. Schambeck, S. Holdenrieder, A. Strötges-Achatz, V. Haselmann, M. Neumaier, J. Erber, A. Priller, S. Yazici, H. Roggendorf, M. Odendahl, T. Tonn, A. Dick, K. Witter, H. Mijočević, U. Protzer, P.A. Knolle, A. Pichlmair, C.S. Crowell, M. Gerhard, E. D’Ippolito, D.H. Busch

Recruitment of Highly Cytotoxic CD8+ T Cell Receptors in Mild SARS-CoV-2 Infection Journal Article

In: Cell Reports, vol. 38, no. 2, pp. 110214, 2022, ISSN: 2211-1247.

Abstract | Links | BibTeX

2021

G. Griffante, F. Gugliesi, S. Pasquero, V. DellÓste, M. Biolatti, A.J. Salinger, S. Mondal, P.R. Thompson, E. Weerapana, R.J. Lebbink, J.A. Soppe, T. Stamminger, V. Girault, A. Pichlmair, G. Oroszlán, D.M. Coen, M. De Andrea, S. Landolfo

Human Cytomegalovirus-induced Host Protein Citrullination is Crucial for Viral Replication Journal Article

In: Nature Communications, vol. 12, no. 1, pp. 3910, 2021, ISSN: 20411723.

Abstract | Links | BibTeX

F.L. Pennemann, A. Mussabekova, C. Urban, A. Stukalov, L.L. Andersen, V. Grass, T.M. Lavacca, C. Holze, L. Oubraham, Y. Benamrouche, E. Girardi, R.E. Boulos, R. Hartmann, G. Superti-Furga, M. Habjan, J. Imler, C. Meignin, A. Pichlmair

Cross-species Analysis of Viral Nucleic Acid Interacting Proteins Identifies TAOKs as Innate Immune Regulators Journal Article

In: Nature Communications, vol. 12, no. 1, pp. 7009, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX

B.T. Laudenbach, K. Krey, Q. Emslander, L.L. Andersen, A. Reim, P. Scaturro, S. Mundigl, C. Dächert, K. Manske, M. Moser, J. Ludwig, D. Wohlleber, A. Kröger, M. Binder, A. Pichlmair

NUDT2 Initiates Viral RNA Degradation by Removal of 5'-phosphates Journal Article

In: Nature Communications, vol. 12, no. 1, pp. 6918, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX

D.S. Fischer, M. Ansari, K.I. Wagner, S. Jarosch, Y. Huang, C.H. Mayr, M. Strunz, N.J. Lang, E. D'Ippolito, M. Hammel, L. Mateyka, S. Weber, L.S. Wolff, K. Witter, I.E. Fernandez, G. Leuschner, K. Milger, M. Frankenberger, L. Nowak, K. Heinig-Menhard, I. Koch, M.G. Stoleriu, A. Hilgendorff, J. Behr, A. Pichlmair, B. Schubert, F.J. Theis, D.H. Busch, H.B. Schiller, K. Schober

Single-cell RNA Sequencing Reveals ex vivo Signatures of SARS-CoV-2-reactive T Cells Through ‘Reverse Phenotyping' Journal Article

In: Nature Communications, vol. 12, no. 1, pp. 4515, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX

A. Holleufer, K.G. Winther, H.H. Gad, X. Ai, Y. Chen, L. Li, Z. Wei, H. Deng, J. Liu, N.A. Frederiksen, B. Simonsen, L.L. Andersen, K. Kleigrewe, L. Dalskov, A. Pichlmair, H. Cai, J. Imler, R. Hartmann

Two cGAS-like Receptors Induce Antiviral Immunity in Drosophila Journal Article

In: Nature, 2021, ISSN: 1476-4687.

Abstract | Links | BibTeX

M. Krivega, C.M. Stiefel, S. Karbassi, L.L. Andersen, N.K. Chunduri, N. Donnelly, A. Pichlmair, Z. Storchová

Genotoxic Stress in Constitutive Trisomies Induces Autophagy and the Innate Immune Response via the cGAS-STING Pathway Journal Article

In: Communications Biology, vol. 4, no. 1, pp. 831, 2021, ISSN: 2399-3642.

Abstract | Links | BibTeX

A. Stukalov, V. Girault, V. Grass, O. Karayel, V. Bergant, C. Urban, D.A. Haas, Y. Huang, L. Oubraham, A. Wang, M.S. Hamad, A. Piras, F.M. Hansen, M.C. Tanzer, I. Paron, L. Zinzula, T. Enghleitner, M. Reinecke, T.M. Lavacca, R. Ehmann, R. Wölfel, J. Jores, B. Kuster, U. Protzer, R. Rad, J. Ziebuhr, V. Thiel, P. Scaturro, M. Mann, A. Pichlmair

Multilevel Proteomics Reveals Host Perturbations by SARS-CoV-2 and SARS-CoV Journal Article

In: Nature, 2021, ISSN: 0028-0836.

Abstract | Links | BibTeX

J. Pei, N.R. Beri, A.J. Zou, P. Hubel, H.K. Dorando, V. Bergant, R.D. Andrews, J. Pan, J.M. Andrews, K.C.F. Sheehan, A. Pichlmair, G.K. Amarasinghe, S.L. Brody, J.E. Payton, D.W. Leung

Nuclear-localized Human Respiratory Syncytial Virus NS1 Protein Modulates Host Gene Transcription Journal Article

In: Cell Reports, vol. 37, no. 2, pp. 109803, 2021, ISSN: 2211-1247.

Abstract | Links | BibTeX

M. Manček-Keber, I. Hafner-Bratkovič, D. Lainšček, M. Benčina, T. Govednik, S. Orehek, T. Plaper, V. Jazbec, V. Bergant, V. Grass, A. Pichlmair, R. Jerala

Disruption of Disulfides Within RBD of SARS-CoV-2 Spike Protein Prevents Fusion and Represents a Target for Viral Entry Inhibition by Registered Drugs Journal Article

In: The FASEB Journal, vol. 35, no. 6, pp. e21651, 2021.

Abstract | Links | BibTeX

D. Stadler, M. Kächele, A.N. Jones, J. Hess, C. Urban, J. Schneider, Y. Xia, A. Oswald, F. Nebioglu, R. Bester, F. Lasitschka, M. Ringelhan, C. Ko, W. Chou, A. Geerlof, M.A. van de Klundert, J.M. Wettengel, P. Schirmacher, M. Heikenwälder, S. Schreiner, R. Bartenschlager, A. Pichlmair, M. Sattler, K. Unger, U. Protzer

Interferon-induced Degradation of the Persistent Hepatitis B Virus cccDNA Form Depends on ISG20 Journal Article

In: EMBO reports, vol. 22, no. 6, pp. e49568, 2021.

Abstract | Links | BibTeX

A.C. Gonzalez-Perez, M. Stempel, E. Wyler, C. Urban, A. Piras, T. Hennig, S. Ganskih, Y. Wei, A. Heim, M. Landthaler, A. Pichlmair, L. Dölken, M. Munschauer, F. Erhard, M.M. Brinkmann, S.M. Horner

The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4/UL5 Transcripts Journal Article

In: mBio, vol. 12, no. 3, pp. e02683-20, 2021.

Abstract | Links | BibTeX

D. Lainšček, T. Fink, V. Forstnerič, I. Hafner-Bratkovič, S. Orehek, Ž. Strmšek, M. Manček-Keber, P. Pečan, H. Esih, Š. Malenšek, J. Aupič, P. Dekleva, T. Plaper, S. Vidmar, L. Kadunc, M. Benčina, N. Omersa, G. Anderluh, F. Pojer, K. Lau, D. Hacker, B.E. Correia, D. Peterhoff, R. Wagner, V. Bergant, A. Herrmann, A. Pichlmair, R. Jerala

A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response Journal Article

In: Vaccines, vol. 9, no. 5, 2021, ISSN: 2076-393X.

Abstract | Links | BibTeX

A.B.C. Schuren, I.G.J. Boer, E.M. Bouma, M.L. Van de Weijer, A.I. Costa, P. Hubel, A. Pichlmair, R.J. Lebbink, E.J.H.J. Wiertz

The UFM1 Pathway Impacts HCMV US2-Mediated Degradation of HLA Class I Journal Article

In: Molecules, vol. 26, no. 2, 2021, ISSN: 1420-3049.

Abstract | Links | BibTeX

2020

K. Krey, A. Babnis, A. Pichlmair

System-based Approaches to Delineate the Antiviral Innate Immune Landscape Journal Article

In: Viruses, vol. 12, no. 10, 2020, ISSN: 19994915.

Abstract | Links | BibTeX

C. Urban, H. Welsch, K. Heine, S. Wüst, D.A. Haas, C. Dächert, A. Pandey, A. Pichlmair, M. Binder

Persistent Innate Immune Stimulation Results in IRF3-Mediated but Caspase-Independent Cytostasis Journal Article

In: Viruses, vol. 12, no. 6, 2020, ISSN: 1999-4915.

Abstract | Links | BibTeX

M. Fabits, V.G. Magalhães, B. Chan, V. Girault, E. Elbasani, E. Rossetti, E. Saeland, M. Messerle, A. Pichlmair, V.J. Lisnić, M.M. Brinkmann

The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription Journal Article

In: Microorganisms, vol. 8, no. 6, 2020, ISSN: 2076-2607.

Abstract | Links | BibTeX

J. Zecha, C.Y. Lee, F.P. Bayer, C. Meng, V. Grass, J. Zerweck, K. Schnatbaum, T. Michler, A. Pichlmair, C. Ludwig, B. Kuster

Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing Journal Article

In: Molecular & Cellular Proteomics, vol. 19, no. 9, pp. 1503–1522, 2020, ISSN: 1535-9476.

Abstract | Links | BibTeX

A. Sib, T.M. Milzarek, A. Herrmann, L. Oubraham, J.I. Müller, A. Pichlmair, R. Brack-Werner, T.A.M. Gulder

Chemoenzymatic Total Synthesis of Sorbicatechol Structural Analogues and Evaluation of Their Antiviral Potential Journal Article

In: ChemBioChem, vol. 21, no. 4, pp. 492-495, 2020.

Abstract | Links | BibTeX

S. Bauernfried, M.J. Scherr, A. Pichlmair, K.E. Duderstadt, V. Hornung

Human NLRP1 is a Sensor for Double-stranded RNA Journal Article

In: Science, 2020, ISSN: 0036-8075.

Abstract | Links | BibTeX

J.D. Wuerth, M. Habjan, M. Kainulainen, B. Berisha, D. Bertheloot, G. Superti-Furga, A. Pichlmair, F. Weber

eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition Journal Article

In: mBio, vol. 11, no. 4, 2020.

Abstract | Links | BibTeX

S. Lampl, M.K. Janas, S. Donakonda, M. Brugger, K. Lohr, A. Schneider, K. Manske, L.E. Sperl, S. Kläger, B. Küster, J. Wettmarshausen, C. Müller, M. Laschinger, D. Hartmann, N. Hüser, F. Perocchi, P. Schmitt-Kopplin, F. Hagn, L. Zender, V. Hornung, C. Borner, A. Pichlmair, H. Kashkar, M. Klingenspor, M. Prinz, S. Schreiner, M. Conrad, P.J. Jost, H. Zischka, K. Steiger, M. Krönke, D. Zehn, U. Protzer, M. Heikenwälder, P.A. Knolle, D. Wohlleber

Reduced Mitochondrial Resilience Enables Non-canonical Induction of Apoptosis after TNF Receptor Signaling in Virus-infected Hepatocytes Journal Article

In: Journal of Hepatology, vol. 73, no. 6, pp. 1347 - 1359, 2020, ISSN: 0168-8278.

Abstract | Links | BibTeX

S. Sadegh, J. Matschinske, D.B. Blumenthal, G. Galindez, T. Kacprowski, M. List, R. Nasirigerdeh, M. Oubounyt, A. Pichlmair, T.D. Rose, M. Salgado-Albarrán, J. Späth, A. Stukalov, N.K. Wenke, K. Yuan, J.K. Pauling, J. Baumbach

Exploring the SARS-CoV-2 Virus-host-drug Interactome for Drug Repurposing Journal Article

In: Nature Communications, vol. 11, no. 1, 2020.

Abstract | Links | BibTeX

2019

A. Gebhardt, V. Bergant, D. Schnepf, M. Moser, A. Meiler, D. Togbe, C. Mackowiak, L.S. Reinert, S.R. Paludan, B. Ryffel, A. Stukalov, P. Staeheli, A. Pichlmair

The Alternative Cap-binding Complex is Required for Antiviral Defense in vivo Journal Article

In: PLOS Pathogens, vol. 15, no. 12, pp. 1-22, 2019.

Abstract | Links | BibTeX

P. Scaturro, A.L. Kastner, A. Pichlmair

Chasing Intracellular Zika Virus Using Proteomics Journal Article

In: Viruses, vol. 11, no. 9, pp. 878, 2019.

Abstract | Links | BibTeX

A. Płaszczyca, P. Scaturro, C.J. Neufeldt, M. Cortese, B. Cerikan, S. Ferla, A. Brancale, A. Pichlmair, R. Bartenschlager

A Novel Interaction Between Dengue Virus Nonstructural Protein 1 and the NS4A-2K-4B Precursor is Required for Viral RNA Replication but not for Formation of the Membranous Replication Organelle Journal Article

In: PLoS Pathogens, vol. 15, pp. e1007736, 2019, ISSN: 1553-7374.

Abstract | Links | BibTeX

P. Hubel, C. Urban, V. Bergant, W.M. Schneider, B. Knauer, A. Stukalov, P. Scaturro, A. Mann, L. Brunotte, H.H. Hoffmann, J.W. Schoggins, M. Schwemmle, M. Mann, C.M. Rice, A. Pichlmair

A Protein-interaction Network of Interferon-stimulated Genes Extends the Innate Immune System Landscape Journal Article

In: Nat. Immunol., 2019, ISSN: 1529-2916.

Abstract | Links | BibTeX

C.J. Neufeldt, M. Cortese, P. Scaturro, B. Cerikan, J.G. Wideman, K. Tabata, T. Moraes, O. Oleksiuk, A. Pichlmair, R. Bartenschlager

ER-shaping Atlastin Proteins Act as Central Hubs to Promote Flavivirus Replication and Virion Assembly Journal Article

In: Nature Microbiology, vol. 4, no. 12, pp. 2416–2429, 2019, ISSN: 2058-5276.

Abstract | Links | BibTeX

2018

P. Scaturro, A. Stukalov, D.A. Haas, M. Cortese, K. Draganova, A. Płaszczyca, R. Bartenschlager, M. Götz, A. Pichlmair

An Orthogonal Proteomic Survey Uncovers Novel Zika Virus Host Factors Journal Article

In: Nature, 2018, ISSN: 1476-4687.

Abstract | Links | BibTeX

P. Scaturro, A. Pichlmair

Oxeiptosis — a Cell Death Pathway to Mitigate Damage Caused by Radicals Journal Article

In: Cell Death Diff., vol. 25, no. 7, pp. 1191-1193, 2018.

Links | BibTeX

D.A. Haas, A. Meiler, K. Geiger, C. Vogt, E. Preuss, G. Kochs, A. Pichlmair

Viral Targeting of TFIIB Impairs de novo Polymerase II Recruitment and Affects Antiviral Immunity Journal Article

In: PLOS Pathogens, vol. 14, no. 4, pp. e1006980, 2018, ISSN: 1553-7374.

Abstract | Links | BibTeX

2017

C. Holze, C. Michaudel, C. Mackowiak, D.A. Haas, C. Benda, P. Hubel, F.L. Pennemann, D. Schnepf, J. Wettmarshausen, M. Braun, D.W. Leung, G.K. Amarasinghe, F. Perocchi, P. Staeheli, B. Ryffel, A. Pichlmair

Oxeiptosis, a ROS-induced Caspase-independent Apoptosis-like Cell-death Pathway Journal Article

In: Nat. Immunol., vol. 19, no. 2, pp. 130-140, 2017.

Abstract | Links | BibTeX

K. Vonderstein, E. Nilsson, P. Hubel, L. Nygård Skalman, A. Upadhyay, J. Pasto, A. Pichlmair, R. Lundmark, A.K. Överby

Viperin Targets Flavivirus Virulence by Inducing Assembly of Non-infectious Capsid Particles Journal Article

In: J Virol, vol. 92, no. 1, pp. e01751-17, 2017, ISSN: 1098-5514.

Abstract | Links | BibTeX

A. Gebhardt, B. Laudenbach, A. Pichlmair

Discrimination of Self and Non-Self Ribonucleic Acids Journal Article

In: J Interferon Cytokine Res., vol. 37, no. 5, pp. 184-197, 2017.

Abstract | Links | BibTeX

J. Willemsen, O. Wicht, J.C. Wolanski, N. Baur, S. Bastian, D.A. Haas, P. Matula, B. Knapp, L. Meyniel-Schicklin, C. Wang, R. Bartenschlager, V. Lohmann, K. Rohr, H. Erfle, L. Kaderali, J. Marcotrigiano, A. Pichlmair, M. Binder

Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening. Journal Article

In: Mol Cell, vol. 65, pp. 403–415.e8, 2017, ISSN: 1097-4164.

Abstract | Links | BibTeX

Y.M. Abbas, B. Laudenbach, S. Martínez-Montero, R. Cencic, M. Habjan, A. Pichlmair, M.J. Damha, J. Pelletier, B. Nagar

Structure of Human IFIT1 with Capped RNA Reveals Adaptable mRNA Binding and Mechanisms for Sensing N1 and N2 Ribose 2'-O methylations Journal Article

In: Proc Natl Acad Sci U S A, vol. 114, pp. E2106–E2115, 2017, ISSN: 1091-6490.

Abstract | Links | BibTeX

G. Brady, D.A. Haas, P.J. Farrell, A. Pichlmair, A.G. Bowie

Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation. Journal Article

In: J Virol, vol. 91, 2017, ISSN: 1098-5514.

Abstract | Links | BibTeX

N. Goonawardane, A. Gebhardt, C. Bartlett, A. Pichlmair, M. Harris

Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions. Journal Article

In: J Virol, vol. 91, 2017, ISSN: 1098-5514.

Abstract | Links | BibTeX

2016

A. Mazouzi, A. Stukalov, A.C. Müller, D. Chen, M. Wiedner, J. Prochazkova, S. Chiang, M. Schuster, F.P. Breitwieser, A. Pichlmair, S.F. El-Khamisy, C. Bock, R. Kralovics, J. Colinge, K.L. Bennett, J.I. Loizou

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN. Journal Article

In: Cell reports, vol. 15, pp. 893–908, 2016, ISSN: 2211-1247.

Abstract | Links | BibTeX

2015

A. Stukalov, A. Pichlmair

Gambling with Flu: "All in" to Maximize Reward Journal Article

In: Cell host microbe, vol. 18, no. 6, pp. 643–645, 2015, ISSN: 1934-6069.

Abstract | Links | BibTeX

A. Gebhardt, M. Habjan, C. Benda, A. Meiler, D.A. Haas, M.Y. Hein, A. Mann, M. Mann, B. Habermann, A. Pichlmair

mRNA Export Through an Additional Cap-binding Complex Consisting of NCBP1 and NCBP3 Journal Article

In: Nat commun, vol. 6, pp. 8192, 2015, ISSN: 2041-1723.

Abstract | Links | BibTeX

L.X. Heinz, C.L. Baumann, M.S. Köberlin, B. Snijder, R. Gawish, G. Shui, O. Sharif, I.M. Aspalter, A.C. Müller, R.K. Kandasamy, F.P. Breitwieser, A. Pichlmair, M. Bruckner, M. Rebsamen, S. Blüml, T. Karonitsch, A. Fauster, J. Colinge, K.L. Bennett, S. Knapp, M.R Wenk, G. Superti-Furga

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity. Journal Article

In: Cell reports, vol. 11, pp. 1919–1928, 2015, ISSN: 2211-1247.

Abstract | Links | BibTeX

G. Brady, D.A. Haas, P.J. Farrell, A. Pichlmair, A.G. Bowie

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-B Activation by Targeting p65 for Degradation. Journal Article

In: J Virol, vol. 89, pp. 8406–8415, 2015, ISSN: 1098-5514.

Abstract | Links | BibTeX

M. Habjan, A. Pichlmair

Cytoplasmic Sensing of Viral Nucleic Acids Journal Article

In: Current opinion in virology, vol. 11, pp. 31–37, 2015, ISSN: 1879-6265.

Abstract | Links | BibTeX

2014

C. Eberle, M. Zayas, A. Stukalov, A. Pichlmair, G. Alvisi, A.C. Müller, K.L. Bennett, R. Bartenschlager, G. Superti-Furga

The Lysine Methyltransferase SMYD3 Interacts with Hepatitis C Virus NS5A and is a Negative Regulator of Viral Particle Production Journal Article

In: Virology, vol. 462-463, pp. 34–41, 2014, ISSN: 1096-0341.

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