The main focus of my laboratory lies in the interaction between viral pathogens and their hosts. We are using a combination of systems biology and hypothesis-driven approaches to understand on a functional and mechanistic basis which proteins and pathways are involved in the host’s antiviral defense. A particular research focus lies in interactions between viral nucleic acids or viral proteins with cellular factors as well as the organization of a general antiviral response mastered by the innate immune system.I studied Veterinary Medicine in Vienna and performed my doctoral thesis (DVM, 2004) at the Institute of Virology of the University of Freiburg (Prof. Otto Haller). Thereafter I joined the Cancer Research UK (LRI – now Francis-Crick Institute) (Prof. Caetano Reis e Sousa) for a PhD (finished 2008) followed by a post-doc at the Center for Molecular Medicine (Prof. Giulio Superti-Furga). In 2011, I established my own laboratory at the Max-Planck Institute of Biochemistry (Munich, Germany) that moved to the Institute of Virology at the Technical University Munich in 2017.
I joined the Pichlmair lab to explore changes in RNA biology that accompany Influenza A infection using a combination of Mass-Spectrometry- and NGS-based approaches. The viruses do not waste time or resources and use evolutionary most advanced molecular biology to influence what's most pivotal in the host's cell - we use this to explore virology as well as basic cell biology. In my spare time, I enjoy art.
I love to solve puzzles and during my masters at Aarhus University (Denmark), I developed a profound interest in putting together the pieces of innate immune signaling mechanisms, an interest I continue to develop in the Pichlmair lab, where I work on elucidating the induction of innate immune signaling by special dinucleotides. Furthermore, I like to experiment in the sweet kitchen using the lab as my test subjects.
Biotech engineer by education (ESBS school, France), I have worked for two years at the Pasteur Institute in HTP assay development before deciding to fully dive into the biology behind and start a PhD. My interest for viral biology brought me to the Pichlmair lab where I use Mass Spectrometry to uncover virus-host interactions. Beside sciences, I enjoy sports as well as the Bavarian Biergartenkultur.
After studying Biochemistry in Tübingen, I was thrilled about the simple yet effective innate immune system and joined the Pichlmair lab in order to discover pathways leading to the degradation of viral nucleic acids. Outside of the lab, I enjoy playing cello and getting prepared for my first triathlon.
After completing a PhD in molecular biology at the Karlsruhe Institute of Technology, I joined the Pichlmair's group as a Lab manager. I try to keep things on track for everyone, and help with technical support when needed. I like to keep people feel good together because the more the merrier.
I joined the Pichlmair lab in 2017 to work on identifying conserved nucleic acid sensing proteins, after studying Medical Biotechnology at Wageningen University. I am slowly working towards outfitting the lab with hand knit winter gear.
After experiences at the Targeted Metabolomics and Proteomics Laboratory (TMPL) of the University of Alabama at Birmingham (USA) as visiting scientist, at the University of Cagliari (Italy) for my doctoral studies and at the Mass-Spectrometry Core Facility of the Max-Planck Institute of Biochemistry (Germany) as an MS engineer, I now make sure that our Mass Spectrometer is always performing as a Ferrari!
After a PhD on tropical arboviruses and antiviral therapies at the University of Heidelberg (Germany), I joined the Pichlmair lab to continue working with my favorite Flaviviruses with advanced Mass-Spectrometry and Systems Biology approaches. In the spare time I'm conditioning the lab to Italian coffee.
PhD in Computational Mathematics (Moscow State University, Russia). Now using mathematical/bioinformatical expertise to develop the methods for the analysis of complex Mass Spectrometry data sets the lab generates. Never did a single experiment in the wet lab.
As a biochemist by training I did my master thesis in mass spectrometry imaging and decided to join the Pichlmair lab for a PhD to apply proteomics and systems biology to deeply explore innate immunology and virology. If you don’t find me in the lab, I’m in the mountains.