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InnateLab

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InnateLab

Immunopathology of Virus Infections
Institute of Virology
TUM School of Medicine
Technical University of Munich
NS1 picture

Congratulations to our collaborators Anna Płaszczyca and Ralf Bartenschlager (Heidelberg) as well as Pietro and Andreas!

Their work on NS1 interaction with the Dengue virus NS4A-2K-4B precursor protein was published in Plos Pathogens. This very novel interaction is essential to drive replication of Dengue virus. Clearly, viral precursor proteins have many more functions than previously anticipated – still a lot to discover!

The paper “A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle” can be found here.

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Institute of Virology,
Immunopathology of viruses
Translatum (Bau 522), Room 22.1.31
Einsteinstr. 25, 81675 Munich

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Prof. Dr. Andreas Pichlmair
Immunopathology of Virus Infections Laboratory, Institute of Virology, Technical University of Munich
Einsteinstr. 25, D-81675 Munich, Germany
tel: +49 (0) 89 4140 9270, email: andreas.pichlmair@tum.de

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