Non-redundant function of the alternative cap complex in antiviral immunity – published in PLOS Pathogens

Congratulations to Anna and Valter for publishing a function role of the alternative CBC!
The alternative cap binding complex consisting of NCBP1 and -3 exports mRNA but is redundant under physiological conditions. However, virus infection or challenge with innate immune stimuli revealed a critical function of the alternative CBC in modulation of the innate immune system. This was particularly evident in NCBP3 deficient mice that showed increased susceptibility to influenza A virus infection.

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Merry Christmas and a Happy New Year!

Happy holidays from all of us from the Schnecke! We had a blast at our yearly Christmasparty last week, with a trip to the christmas market, a big potluck, a dice gift exchange, a glove throwing competition, as well as lots of dancing!

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Congratulations Dr. Philip!

Congratulations to Dr. Hubel!! Philipp defended his PhD thesis in a splendid manner. Having first authored one paper in Nature Immunology and PLOS Pathogens and co-authored several other manuscripts he succeded with the best possible grade! Well done Philipp…. you just lost your hair on the way.

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Goodbye Hannah!

After three years in the lab with us it’s time to say goodbye to Hannah. You’ve helped so many people during your time here, I’d bet you’ve affected almost every project we worked on.
Best of luck with your Masters and for everything else the future holds!

Read More »

Non-redundant function of the alternative cap complex in antiviral immunity – published in PLOS Pathogens

Congratulations to Anna and Valter for publishing a function role of the alternative CBC!
The alternative cap binding complex consisting of NCBP1 and -3 exports mRNA but is redundant under physiological conditions. However, virus infection or challenge with innate immune stimuli revealed a critical function of the alternative CBC in modulation of the innate immune system. This was particularly evident in NCBP3 deficient mice that showed increased susceptibility to influenza A virus infection.

Read More »

Merry Christmas and a Happy New Year!

Happy holidays from all of us from the Schnecke! We had a blast at our yearly Christmasparty last week, with a trip to the christmas market, a big potluck, a dice gift exchange, a glove throwing competition, as well as lots of dancing!

Read More »

Congratulations Dr. Philip!

Congratulations to Dr. Hubel!! Philipp defended his PhD thesis in a splendid manner. Having first authored one paper in Nature Immunology and PLOS Pathogens and co-authored several other manuscripts he succeded with the best possible grade! Well done Philipp…. you just lost your hair on the way.

Read More »

Goodbye Hannah!

After three years in the lab with us it’s time to say goodbye to Hannah. You’ve helped so many people during your time here, I’d bet you’ve affected almost every project we worked on.
Best of luck with your Masters and for everything else the future holds!

Read More »