A great collaborative work observing how long the SARS-CoV-2-specific CD8+ T cell response is lasting, and used engineered T cells to define highly functional cytotoxic signature.

We identified Nudix hydrolase 2 (NUDT2) as one key player to clear cells from viral triphosphorylated RNA (PPP-RNA).

We used conservation of binding properties over evolution to identify proteins that are relevant for innate immunity.

This construct can neutralize all SARS coronaviruses at the picomolar range!

In a joint collaborative battle Daisy Leung pubished a mechanism employed by NS1 of RSV to modulate gene transcription. We identified the critical binding partner of NS1 involved in this process.

Our collaborators from the Landolfo Lab discovered that HCMV infection triggers viral and host protein citrullination. We helped to characterize the consequences on IFIT1 antiviral function.