ISG20, a host nuclease that degrades HBV’s cccDNA
July 23, 2021
Our collaboration with the Protzer Lab helps identify a new anti-HBV host factor, ISG20!
Immunopathology of Virus Infections
Our collaboration with the Protzer Lab helps identify a new anti-HBV host factor, ISG20!
Scientific community can use these deep and comprehensive data to understand COVID-19 molecular mechanisms.
Congratulations to our collaboration partners Stefan Bauernfried and Veit Hornung with whom we could identify NLRP1 as dsRNA sensor to activate the inflammasome leading to pyroptosis.
Check out our new review „System-Based Approaches to Delineate the Antiviral Innate Immune Landscape“, recently published in Viruses.
Medium throughput functional screens and single cell genomics
Congratulations to our collaborators of the Jan Baumbach lab! In a great effort they managed to generate a tool that uses interactome data to identify suitable drugs that may be active against SARS-CoV-2 – now accepted in Nature Communications. They generated a website that serves as highly suitable interface to browse interactomes and to identify suitable drugs (https://exbio.wzw.tum.de/covex/). Fantastic work – congratulations to the manuscript!
Prof. Dr. Andreas Pichlmair
Immunopathology of Virus Infections Laboratory, Institute of Virology, Technical University of Munich
Einsteinstr. 25, D-81675 Munich, Germany
tel: +49 (0) 89 4140 9270, email: andreas.pichlmair@tum.de
https://www.mri.tum.de/datenschutz
Der Datenschutzbeauftragte des Klinikums ist unter Klinikum rechts der Isar, Stabsstelle Datenschutz, 81664 München oder unter 089/4140-0 oder datenschutz@mri.tum.de zu erreichen.
Der Datenschutzbeauftragte der TU München ist unter beauftragter@datenschutz.tum.de zu erreichen.